Martin S Angst Selected Research

Surgical Wound

1/2013	Postoperative subcutaneous instillation of low-dose ketorolac but not hydromorphone reduces wound exudate concentrations of interleukin-6 and interleukin-10 and improves analgesia following cesarean delivery.
10/2012	Collecting and measuring wound exudate biochemical mediators in surgical wounds.
12/2010	The role of interleukin-1 in wound biology. Part II: In vivo and human translational studies.
12/2010	Continuous subcutaneous instillation of bupivacaine compared to saline reduces interleukin 10 and increases substance P in surgical wounds after cesarean delivery.
10/2008	Collecting and measuring nociceptive and inflammatory mediators in surgical wounds.
10/2007	Morphine reduces local cytokine expression and neutrophil infiltration after incision.
6/2006	Blockade of the complement C5a receptor reduces incisional allodynia, edema, and cytokine expression.

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Martin S Angst Research Topics

Disease

38	Pain (Aches) 01/2022 - 10/2002
14	Hyperalgesia 06/2015 - 03/2003
13	Wounds and Injuries (Trauma) 03/2024 - 10/2007
7	Surgical Wound 01/2013 - 06/2006
5	Postoperative Pain 06/2015 - 11/2004
4	Chronic Pain 01/2020 - 01/2006
3	Respiratory Insufficiency (Respiratory Failure) 07/2012 - 03/2009
3	Inflammation (Inflammations) 07/2012 - 06/2006
3	Back Pain (Backache) 03/2010 - 01/2006
2	Infections 01/2024 - 08/2017
2	Pre-Eclampsia (Preeclampsia) 12/2022 - 01/2020
2	Cancer Pain 01/2022 - 09/2010
2	COVID-19 01/2022 - 02/2021
2	Low Back Pain (Lumbago) 08/2012 - 03/2010
2	Drug-Related Side Effects and Adverse Reactions 09/2010 - 01/2006
1	Substance-Related Disorders (Drug Abuse) 01/2022
1	Obstetric Labor Complications 01/2021
1	Sepsis (Septicemia) 01/2020
1	Ischemic Stroke 01/2019
1	Neurocognitive Disorders (Clerambault Syndrome) 12/2018
1	Critical Illness (Critically Ill) 08/2017
1	Arterial Occlusive Diseases (Arterial Occlusive Disease) 10/2012
1	Thrombophilia 10/2012
1	Knee Osteoarthritis 07/2012
1	Pruritus (Itching) 07/2012
1	Nausea 07/2012
1	Sunburn 12/2010
1	Burns 11/2010
1	Xerostomia 09/2010
1	Communicable Diseases (Infectious Diseases) 09/2010

Drug/Important Bio-Agent (IBA)

25	Opioid Analgesics (Opioids)IBA 01/2022 - 03/2003
16	Analgesics (Analgesic Drugs)IBA 01/2020 - 11/2003
10	Biomarkers (Surrogate Marker)IBA 01/2024 - 10/2008
10	CytokinesIBA 10/2012 - 06/2006
7	Remifentanil (Ultiva)FDA Link 06/2015 - 03/2003
5	Morphine (MS Contin)FDA LinkGeneric 08/2012 - 01/2006
4	InterleukinsIBA 01/2013 - 07/2008
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2010
3	Interleukin-8 (Interleukin 8)IBA 01/2013 - 07/2008
3	Interleukin-10 (Interleukin 10)IBA 01/2013 - 07/2008
3	ChemokinesIBA 12/2010 - 11/2010
3	Substance PIBA 12/2010 - 07/2008
2	LigandsIBA 01/2022 - 02/2021
2	Blood Proteins (Serum Proteins)IBA 01/2022 - 02/2021
2	GlucocorticoidsIBA 01/2020 - 01/2020
2	Interleukin-12 (IL 12)IBA 01/2013 - 07/2008
2	Hydromorphone (Dilaudid)FDA LinkGeneric 01/2013 - 10/2002
2	Interleukin-6 (Interleukin 6)IBA 01/2013 - 07/2008
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2013 - 07/2008
2	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 01/2013 - 12/2010
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2013 - 07/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 07/2008
2	Local AnestheticsIBA 01/2013 - 12/2010
2	Interleukin-2 (IL2)IBA 01/2013 - 07/2008
2	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 12/2010 - 07/2008
2	Interleukin-1 (Interleukin 1)IBA 12/2010 - 12/2010
2	Dinoprostone (PGE2)FDA Link 11/2010 - 07/2008
2	Nerve Growth Factor (NGF)IBA 11/2010 - 07/2008
2	Interferon-gamma (Interferon, gamma)IBA 03/2010 - 07/2008
2	Fentanyl (Sublimaze)FDA LinkGeneric 04/2007 - 11/2003
1	Cocaine (Cocaine HCl)IBA 01/2022
1	Amphetamine (Amfetamine)FDA LinkGeneric 01/2022
1	Cyclooxygenase InhibitorsIBA 01/2021
1	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 01/2021
1	Nefopam (Ajan)IBA 01/2021
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2021
1	Dipyrone (Metamizole)IBA 01/2021
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2019
1	Immunoglobulin M (IgM)IBA 01/2019
1	Immunoglobulins (Immunoglobulin)IBA 01/2019
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 01/2019
1	Arginine (L-Arginine)FDA Link 08/2017
1	Carrier Proteins (Binding Protein)IBA 09/2014
1	Adenosine (Adenocard)FDA LinkGeneric 09/2014
1	InterferonsIBA 01/2013
1	Dihydrotachysterol (AT 10)IBA 01/2013
1	KetorolacIBA 01/2013
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2013
1	A-factor (Streptomyces)IBA 10/2012
1	Opioid Receptors (Opioid Receptor)IBA 07/2012
1	Propranolol (Inderal)FDA LinkGeneric 05/2012
1	Adrenergic Receptors (Adrenergic Receptor)IBA 05/2012
1	Capsaicin (Zostrix)FDA Link 03/2011
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2010
1	salicylhydroxamic acid (SHAM)IBA 11/2010
1	Ketamine FDA LinkGeneric 09/2010
1	Aggrecans (Aggrecan)IBA 07/2010
1	Fibronectins (Fibronectin)IBA 07/2010
1	SteroidsIBA 10/2009

Therapy/Procedure

7	Therapeutics 01/2022 - 01/2006
7	Analgesia 01/2013 - 11/2003
1	Orthopedic Procedures 03/2024
1	Induced Labor 01/2021
1	Anesthesia 12/2018
1	Precision Medicine 09/2016
1	Lasers (Laser) 03/2011
1	Perioperative Period 12/2010
1	Spinal Anesthesia 12/2010
1	Nerve Block (Nerve Blocks) 11/2010
1	Drug Therapy (Chemotherapy) 09/2010